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Extreme High Blood Sugar


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Extreme high blood sugar can lead to two life-threatening conditions:

Hyperosmolar Hyperglycemic Nonketotic Syndrome (HHNS)

This is a life-threatening condition most often seen in elderly people. HHNS can happen to people with either type 1 or type 2 diabetes, but it occurs more often in people with type 2. HHNS is usually caused by an illness or infection.

In HHNS, blood sugar levels rise, and the body tries to get rid of the excess sugar by passing it into your urine. You will make a lot of urine at first. Later, you may not have to go to the bathroom as often, and your urine becomes very dark. This might make you very thirsty. It is important, even if you are not thirsty, to drink liquids. This will help keep you from getting dehydrated.

If HHNS continues, the severe dehydration will lead to seizures, coma, and eventually death. HHNS may take days or even weeks to develop. Know the warning signs of HHNS:

  • Very high blood sugar level (over 600 mg/dL)

  • Extreme thirst (Although this may gradually disappear.)

  • Dry mouth

  • Warm, dry skin that does not sweat

  • High fever

  • Sleepiness or confusion

  • Loss of vision

  • Hallucinations (Seeing or hearing things that are not there.)

  • Weakness on one side of the body

Test your blood sugar, if symptoms appear. Drink fluids if you can. Call your doctor right away.

The best way to avoid HHNS is to check your blood sugar regularly. You can also work with your doctor to develop a sick-day plan, so that you can reduce the risk of HHNS caused by sickness.

Ketoacidosis

Ketoacidosis is a serious condition that can lead to diabetic coma or even death. Ketoacidosis may happen to people with type 1 diabetes. It occurs rarely in people with type 2 diabetes.

Ketoacidosis means dangerously high levels of ketones. Ketones are acids that build up in the blood. They appear in the urine when your body doesn’t have enough insulin. They are a warning sign that your diabetes is out of control or that you are getting sick.

Treatment for ketoacidosis usually takes place in the hospital. But you can help prevent ketoacidosis by learning the warning signs and checking your urine for ketones and blood sugar regularly. Ask your doctor when and how you should test for ketones.

Many experts advise to check your urine for ketones when your blood glucose is more than 240 mg/dL. When you are ill (when you have a cold or the flu, for example), check for ketones every four to six hours. And, check every four to six hours when your blood glucose is more than 240 mg/dL.

Also, check for ketones when you have any symptoms of ketoacidosis. Some of the first symptoms are:

  • Thirst or a very dry mouth

  • Frequent urination

  • High blood glucose (sugar) levels

  • High levels of ketones in the urine

Next, some other symptoms may appear:

  • Constantly feeling tired


  • Dry or flushed skin


  • Nausea, vomiting, or abdominal pain (Vomiting can be caused by many illnesses, not just ketoacidosis. If vomiting continues for more than two hours, contact your healthcare provider.)


  • A hard time breathing (short, deep breaths)


  • Fruity odor on breath


  • A hard time paying attention or confusion

If you have these symptoms, test your blood sugar and your urine ketones.

Call your doctor at once if:

  • Your urine tests show large ketones.


  • Your urine tests show large ketones and your blood glucose level is high.


  • You have vomited more than twice in four hours and your urine tests show high ketones.

Also of Interest

  Create your personal Type 2 Diabetes Action Plan (PDF Format) with your doctor.

  Learn how to help a friend or family member who has type 2 diabetes.


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